Matrix interference or matrix effect, typically refers to the components of a particular matrix (such as soil, water or air etc.) having an an effect on the way an analysis is conducted or the quality of the results obtained from said analysis.
Interference's could include but not limited to:
- High concentrations of target and non-target analytes.
- Compounds or analytes that cause Instrument detector interference.
- Sample components causing coloured or turbid extracts and digests.
- Analytes or sample chemistry that reacts with analysis reagents.
- Matrix interference can also be caused by organic and/inorganic compounds found within the sample.