Detection limits raised due to matrix interference.

Modified on: Tue, 7 May, 2019 at 12:05 PM

Matrix interference could include compounds directly affecting instrument sensitivity.  It could also be target or non-target compounds masking the signal of those being targeted.  High concentrations of target analytes could also be a cause for dilution.  Heavily coloured extracts could also be cause for interference.

Dilution of the sample matrix is the primary approach to combat or decrease the impact of interferences and are the typical cause for raised RDLs.  

A dilution directly affects the RDL or detection limit by the same magnitude .  e.g. if a 5 x dilution was performed, the RDL is also raised by a factor of 5.

The dilution ensure instrument functionality and confidence in the reported data.  

With your Bureau Veritas Laboratories Job number reference, please contact one of our service team to discuss what options might be available for additional analysis or further investigation.

Did you find it helpful? Yes No

Send feedback
Sorry we couldn't be helpful. Help us improve this article with your feedback.